I have a medical treatment terminology question?

January 6th, 2009
  • I have had a hi white count and im being sent to a benine hemotology center.what does chronic leucosytosis mean? and what does ov3 treatment mean?can anyone help answer these questions.


  • Leukocytosis, a common laboratory finding, is most often due to relatively benign conditions (infections or inflammatory processes). Much less common but more serious causes include primary bone marrow disorders. The normal reaction of bone marrow to infection or inflammation leads to an increase in the number of white blood cells, predominantly polymorphonuclear leukocytes and less mature cell forms (the "left shift"). Physical stress (e.g., from seizures, anesthesia or overexertion) and emotional stress can also elevate white blood cell counts. Medications commonly associated with leukocytosis include corticosteroids, lithium and beta agonists. Increased eosinophil or basophil counts, resulting from a variety of infections, allergic reactions and other causes, can lead to leukocytosis in some patients. Primary bone marrow disorders should be suspected in patients who present with extremely elevated white blood cell counts or concurrent abnormalities in red blood cell or platelet counts. Weight loss, bleeding or bruising, liver, spleen or lymph node enlargement, and immunosuppression also increase suspicion for a marrow disorder. The most common bone marrow disorders can be grouped into acute leukemias, chronic leukemias and myeloproliferative disorders. Patients with an acute leukemia are more likely to be ill at presentation, whereas those with a chronic leukemia are often diagnosed incidentally because of abnormal blood cell counts. White blood cell counts above 100,000 per mm3 (100 X 109 per L) represent a medical emergency because of the risk of brain infarction and hemorrhage.


  • Leukocytosis (high white blood cell count)
    Leukocytosis is an increased number of leukocytes(leukocyte count), or white blood cells (WBCs) above the normal range for age and sex, in the blood. For adults this is > 11.0 x109/L leukocytes. The WBCs are the blood cells responsible for the immune response, the fighting of infection. There are many different kinds of WBCs, each with their own particular function. WBCs are produced in the bone marrow, circulate for a time in the blood, and leave the blood to perform their function in the tissues. WBC levels may increase due to increased marrow production or decreased exit from the blood to the tissues.

    An increase in the WBC count is a typical response to noxious stimuli and is usually part of an inflammatory reaction. A leukocytosis is frequently accompanied by cytologic abnormalities, such as toxic granulation or Dohle bodies. Although all or individual types of leukocytes (neutrophils, lymphocytes, etc.)

    Causes of a high white blood cell count (leukocytosis) include:

    * Infection
    * Use of certain medications, such as corticosteroids, antibiotics or anti-seizure drugs
    * Severe physical or emotional stress
    * Chronic bone marrow diseases such as a myeloproliferative disorder
    * Acute or chronic leukemia
    * Tissue damage, such as from burns

    OV-3 treatment is used for patients diagnosed with Ovarian Cancer.







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